High Quality API Powder Apixaban Intermediate CAS 27143-07-3

• Customization: Available
• Powder: Yes
• Customized: Ready to Ship
• Model NO.: CAS 27143-07-3
• Certification: GMP, ISO 9001, USP, BP
• Suitable for: Elderly, Adult
• State: Powder
• Purity: >99%
• Intermediate: Apixaban-2
• Other Name: (Arry-470)
• Sample: Free
• Application: for Antibacteria
• Heavy Metal: 10ppm
• Impurity: 0.01%
• Residual Solvent: Ethanol
• Annul Sales: 2000kg
• Capacity: 2500kg
• Stock: 2.00kg
• Water: 0.01%
• Market: India
• Ever Exported?: Yes
• Volume: 200kg
• Experience: 10years
• Transport Package: Air
• Specification: JP
• Trademark: jianfeng
• Origin: Shandong
• HS Code: 2939000000

Product Description

 

Factory supply Best quality Apixaban Intermediate 27143-07-3 545445-44-1 bulk order

Product Description

 

CAS: 503612-47-3

MF: C₂₅H₂₅N₅O₄

MW: 459.5

Other name: BMS-562247-01

Description: Apixaban powder cas 503612-47-3 is an anticoagulant medication used to treat and prevent blood clots and to prevent stroke in people with nonvalvular atrial fibrillation. Specifically it is used to prevent blood clots following hip or knee replacement and in those with a history of prior clots. It is used as an alternative to wa11rfarin and does not require monitoring by blood tests.

 

Product Parameters

 

Test items	Standard	Results
Appearance	White to off-white powder	Conform
Melting Point	145-149ºC	145~148ºC
HPLC Assay	≥99.0%	>99.72%
LC/MS	Conformity with the structure	Conform
NMR	Conformity with the structure	Conform
Related substance	Total impurities≤1.0%	<1.0%
	Any impurity≤0.1%	<0.1%
Loss of drying	≤0.5%	0.3%

Our company sells more than 5 tons of Apixaban Intermediate to domestic export trading companies every year.
In recent years, we have started to do foreign market. Please contact me to obtain the factory price.

1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid ethyl ester					503614-91-3	Apixaban intermediate
Acetic acid, 2-chloro-2-[2-(4-methoxyphenyl)hydrazinylidene], ethyl ester					27143-07-3	Apixaban intermediate
2(1H)-pyridine,3-chloro-5,6-dihydro-1-(4-nitrophenyl)					536760-29-9	Apixaban intermediate
3-Morpholin-4-yl-1-[4-(2-oxopiperidin-1-yl)phenyl]-5,6-dihydro-1H-pyridin-2-one					545445-44-1	Apixaban intermediate
3-(4-Morpholinyl)-1-(4-nitrophenyl)-5,6-dihydro-2(1H)-pyridinone					503615-03-0	Apixaban intermediate
Ethyl 1-(4-methoxyphenyl)-6-(4-nitrophenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3					536759-91-8	Apixaban intermediate
ethyl 6-(4-aMinophenyl)-1-(4-Methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate					503615-07-4	Apixaban intermediate
1-(4-AMinophenyl)-5,6-dihydro-3-(4-Morpholinyl)-2(1h)-pyridinone					1267610-26-3	Apixaban intermediate

Apixaban is an anticoagulant used to reduce the risk of stroke and systemic embolism in patients with non valvular atrial fibrillation. 

A key component in helping our customers be first to market is a responsive supply chain.
We achieve this by making sure that all our facilities are operating efficiently and to the latest standards of quality, safety, and productivity.
A strong interconnect between business and factories allows for a quick reaction to dynamic market changes, so that we can avert shortages and meet sudden surges in demand.

Apixaban is a selective inhibitor of FXa. It does not require antithrombin III for antithrombotic activity.
Apixaban inhibits free and clot-bound FXa, and prothrombinase activity. Apixaban has no direct effect on platelet aggregation, but indirectly inhibits platelet aggregation induced by thrombin.
By inhibiting FXa, apixaban decreases thrombin generation and thrombus development.

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