Customization: | Available |
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Powder: | Yes |
Customized: | Customized |
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Product introduction
Product name: 5-aMino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile
Cas: 330792-70-6
MF: C16H12N4O
Appearance: Light yellow to off-white powder
Assay: ≥98.5%
Maxium single impurity: ≤1.0%
Total impurity: ≤0.2%
Loss on drying: ≤1.0%
Residue on ignition: ≤0.2%
Heavy metals: ≤20ppm
Molecular Weight: 276.29
Application: 3-Amino-5-(4-phenoxyphenyl)-4-cyano-1H-pyrazole is an intermediate used in the synthesis of ibrutinib, which is a Bruton's tyrosine kinase (BTK) inhibitor for the treatment of chronic lymphocytic leukemia (CChemicalbookLL) and mantle cell lymphoma (MCL). Ibrutinib can target BTK necessary for the formation, differentiation, information transmission and survival of B lymphocytes, irreversibly inhibit the activity of BTK, and effectively inhibit the proliferation and survival of tumor cells.
Specification
TESTS |
SPECIFICATIONS |
RESULTS |
|
Appearance |
Light yellow to off-white powder |
Off-white poeder |
|
Related substance |
Maxium single impurity |
≤1.0% |
0.33% |
Total impurity |
≤2.0% |
0.65% |
|
Loss on drying |
≤1.0% |
0.49% |
|
Residue on ignition |
≤0.2% |
Conforms |
|
Heavy metal |
≤20ppm |
Conforms |
|
Assay |
≥98.5% |
99.35% |
♦ 25KG/drum,or according to your requirement.
♦ Transit could be DHL,UPS,TNT,EMS,Fedex,and so on.
♦ For mass orders, it will be delivered by air or sea.
♦ Depending on your location, please allow 1-5 business days for your order to arrive.
♦ For small order, please expect 3-7 days by UPS DHL EMS.
♦ For mass order, please allow 5-8 days by Air, 15-30 days by Sea.
Q1: Are you a manufacturer?
--We are based in Shandong, China, start from 2011, selling to America market(70.00%) and other market(30.00%). There are total about 50-100 people in our office.
Q2: What can you buy from us?
--- NMN and Tianeptine sodium/acid/sulfate are our main product. We also produce other APIs and intermediates.
Q3: How about delivery lead time?
-- We have our own DHL, UPS and Fedex accounts, and enjoy the lowest discounts. At the same time, we also have professional shipping agents to assist us in transportation. Delivery lead time is about 3-5 days after payment confirmed.
Q3: How long will it take to receive the parcel?
-- The time is 5-7 days for the US market and 10-15 days for the others.
Q4: Which kind of payment terms do you accept?
---For small order,you can pay by T/T, Western Union or Paypal, commercial order by T/T to our company account.
Q5: What are your strengths?
---Factory price direct selling, under the premise of ensuring quality, give you the lowest price. Save cost for you, leave bigger profit space for you.