Product Description
Product name: Baricitinib phosphate salt;
CAS: 1187595-84-1
MF: C16H20N7O6PS
MW: 469.412061
Application: Baricitinib phosphate (LY3009104 phosphate; INCB028050 phosphate) is a selective orally bioavailable JAK1/JAK2 inhibitor with IC50 of 5.9 nM and 5.7 nM, respectively. Baricitinib phosphate (INCB028050 phosphate) treatment, compares with vehicle, inhibits the increase in hind paw volumes during the 2 wk of treatment by 50% at a dose of 1 mg/kg and >95% at doses of 3 or 10 mg/kg. Because baseline paw volume measurements are taken on treatment day 0-in animals with significant signs of disease-it is possible to have >100% inhibition in animals showing marked improvement in swelling. Baricitinib (0.7 mg/day) treated mice exhibits substantially reduced inflammation as assessed by H&E staining, reduced CD8 infiltration, and reduced MHC class I and class II expression when compared with vehicle-control treated mice. CD8+NKG2D+ cells, critical effectors of disease in murine and human alopecia areata (AA), are greatly diminished in Baricitinib treated mice compare with vehicle control treated mice.
Detailed Photos
Packaging & Shipping
♦ 25KG/drum,or according to your requirement.
♦ Transit could be DHL,UPS,TNT,EMS,Fedex,and so on.
♦ For mass orders, it will be delivered by air or sea.
♦ Depending on your location, please allow 1-5 business days for your order to arrive.
♦ For small order, please expect 3-7 days by UPS DHL EMS.
♦ For mass order, please allow 5-8 days by Air, 15-30 days by Sea.
Our Advantages
1. Goverment support guarantees good company credibility and finance safe.
2. Jianfeng Chemical is confident at the product quality, and would like t o supply free sample.
3. Factory locates in national new material industrial park where guarantees safe and continuous production.
4. More than 10 years chemical production and exporting experience, and good relationship with customs and ship agents, which guarantee fast and safe export.
5. Professional R&D technology team and equipment which keep products quality better and better.
6. Timely afterservice resolves your worry for international trade.
Company Profile
Business Type: Manufacturer
Location: Shandong, China (Mainland)
Main Products:
Antifungal,Osteoporosis,Anticancer,Psychiatric,Antidiabetics&Antihypertensive,Anesthesia,Cardio-Cerebral -Vascular,Urinary system and so on ,also intermediate chemicals
Total Employees: 50 - 100 People
Total Annual Revenue: US$2.5 Million - US$5 Million
Year Established: 2011
Jinan Jianfeng Chemical Co.,Ltd .is a leading research-driven family-managed pharmaceutical company. In the principle of "Quality Oriented", Jianfeng passed the certification of ISO9001:2008 Quality Management System. The products meet USP, EP, JP and CP standards and are available not only in China but also in the US, Germany, Canada, Japan, etc. To meet market demands, Jianfeng set up one R&D center, two GMP workshops and three pharmaceutical & chemical factories.
"Honesty, practicality, innovation, development" are our values. Jianfeng would like to cooperate with you with high quality products and competitive price.
Certifications
FAQ
Q1: Are you a manufacturer?
--.Jinan Jianfeng Chemical Co.Ltd, founded on 2011, is a leading research-driven family-managed pharmaceutical company. In the principle of "Quality Oriented", Jianfeng passed the certification of ISO9001:2008 Quality Management System. The products meet USP, EP, JP and CP standards and are available not only in China but also in the US, Germany, Canada, Japan, etc.
Q2: When will the product be shipped after payment?
---The parcel will be get ready and shipped within 2 days.
Q3: How long will it take to receive the parcel?
--5-7 days for the US market; 10-15 days for the others.
Q4: Which kind of payment terms do you accept?
---For small order,you can pay by T/T, trade assurance or Paypal, commercial order by T/T to our company account.
Q5: What can I do if I don't have the ability to clear the custom?
--We got experience after doing export for many years, so don't worry we can handle that.
Q6: Can I get some samples?
---Yes, we can supply the free sample, but the shipping cost be paid by customers.
Q7: How to contact us ?
---You can chat with us by Trade manager, WhatsApp&Skype Online.
You can choose your interested products and send inquiry to us. You can dial our telephone directly or send email to me, you will get our reply.
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