Raw Material Apixaban Intermediate Apixaban 503614-91-3

• Customization: Available
• Powder: Yes
• Customized: Customized
• Model NO.: JF002
• Suitable for: Elderly, Adult
• State: Powder
• Purity: >99%
• Intermediate: Apixaban-2
• Other Name: (Arry-470)
• Sample: Free
• Supplier: Apixaban Factory
• Heavy Metal: 10ppm
• Impurity: 0.01%
• Ros: Yes
• Annul Sales: 2000kg
• Capacity: 25000kg
• Stock: 2.00kg
• Water: 0.01%
• Market: Globle
• Ever Exported?: Yes
• Volume: 200kg
• Experience: 10years
• Transport Package: Air
• Specification: JP
• Trademark: jianfeng
• Origin: Shandong
• HS Code: 2939000000

Product Description

Raw Material Apixaban Intermediate  Apixaban 503614-91-3

 

1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid ethyl ester					503614-91-3	Apixaban intermediate
Acetic acid, 2-chloro-2-[2-(4-methoxyphenyl)hydrazinylidene], ethyl ester					27143-07-3	Apixaban intermediate
2(1H)-pyridine,3-chloro-5,6-dihydro-1-(4-nitrophenyl)					536760-29-9	Apixaban intermediate
3-Morpholin-4-yl-1-[4-(2-oxopiperidin-1-yl)phenyl]-5,6-dihydro-1H-pyridin-2-one					545445-44-1	Apixaban intermediate
3-(4-Morpholinyl)-1-(4-nitrophenyl)-5,6-dihydro-2(1H)-pyridinone					503615-03-0	Apixaban intermediate
Ethyl 1-(4-methoxyphenyl)-6-(4-nitrophenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3					536759-91-8	Apixaban intermediate
ethyl 6-(4-aMinophenyl)-1-(4-Methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate					503615-07-4	Apixaban intermediate
1-(4-AMinophenyl)-5,6-dihydro-3-(4-Morpholinyl)-2(1h)-pyridinone					1267610-26-3	Apixaban intermediate

Apixaban is an anticoagulant used to reduce the risk of stroke and systemic embolism in patients with non valvular atrial fibrillation. 
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Apixaban is a selective inhibitor of FXa. It does not require antithrombin III for antithrombotic activity. Apixaban inhibits free and clot-bound FXa, and prothrombinase activity. Apixaban has no direct effect on platelet aggregation, but indirectly inhibits platelet aggregation induced by thrombin. By inhibiting FXa, apixaban decreases thrombin generation and thrombus development

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