Raw Material CAS 131707-25-0 Powder Arbidol HCl

• Powder: Yes
• Customized: Non-Customized
• Certification: GMP, ISO 9001, USP, BP
• Suitable for: Adult
• State: Solid
• Purity: >99%
• Model NO.: 131707-25-0
• Key Word: Arbidol HCl Powder
• Assay(HPLC): 98.5%Min
• Chemical Name: Arbidol
• Synonym: Umifenovir Hydrochloride
• Transport Package: Foil Bag Drum
• Specification: 10g 100g 1kg 2kg 5kg 10kg 25kg
• Trademark: Jinan Jianfeng
• Origin: China
• Production Capacity: 500kg/Month

Product Description

 Raw Material  CAS 131707-25-0 Powder Arbidol HCl

Product Description

Cas: 131707-23-8
Other names: ARB, Arbidol, Umifenovir hydrochloride
MF: C22H26BrClN2O3S
Molecular Weight: 513.87544
Appearance: White or off-white crystalline powder
Residue on ignition: ≤0.2%
Assay(HPLC): 98.5%

Description: Arbidol HCl powder cas 131707-23-8 (Umifenovir) is a broad-spectrum antiviral compound that blocks viral fusion, used in treatment of influenza and other respiratory viral infections.

Other chemical names: Arbidol hydrochloride hydrate, 6-Bromo-4-[(dimethylamino)methyl]-5-hydroxy-1-methyl-2-[(phenylthio)methyl]-,1H-indole-3-carboxylic Acid Ethyl Ester Hydrochloride

Application: Arbidol HCl powder cas 131707-23-8 inhibits the cell entry of HCV pseudoparticles of genotypes 1a, 1b, and 2a in a dose-dependent fashion.
Arbidol HCl powder cas 131707-23-8 also displays a dose-dependent inhibition of HCV membrane fusion, as assayed by using HCV pseudoparticles (HCVpp) and fluorescent liposomes.  
Arbidol HCl powder cas 131707-23-8 is found to present potent inhibitory activity against enveloped and non-enveloped RNA viruses, including FLU-A, RSV, HRV 14 and CVB3 when added before, during, or after viral infection, with IC50 ranging from 2.7 to 13.8 mg/mL.
Arbidol HCl powder cas 131707-23-8 shows selective antiviral activity against AdV-7, a DNA virus, only when added after infection (therapeutic index (TI) = 5.5).
Arbidol HCl powder cas 131707-23-8 induces changes to viral mRNA synthesis of the PB2, PA, NP, NA, and NS genes in MDCK cultures infected with influenza A/PR/8/34.

Detailed Photos

Function:
Arbidol hydrochloride (ARB) is a small monocular compound used as a broad-spectrum inhibitor of influenza A and B virus, parainfluenza virus, respiratory syncytial virus, adenovirus, coxsackievirus and hepatitis C virus infection. It is less likely to induce drug resistance than other compounds, such as adamantine and oseltamivir. However, its mechanism is complicated: earlier reports indicated that ARB could inhibit the membrane fusion of enveloped viruses in vitro and strengthen the interactions between virus glycoprotein and the membrane of host during the endocytosis. However, this scenario cannot explain the antiviral activity of ARB on non-enveloped viruses that directly release genomes into the cytosol without a membrane fusion process14. Moreover, a recent study has found that ARB exhibited only 6% to 8% inhibition of IFV viral fusion from measurements of hemolysis analysis in vitro. It seems that the antiviral efficacy of ARB does not completely depend on the anti-fusion activity.
 

 

Product Parameters

 

Items of analysis	Standard	Result of analysis
Description	White or creamy or siskin-green crystalline powder	Conforms
Solubility	Slightly soluble in chnd 96% ethyl alcohol, practically insoluble in water	Conforms
Identification	IR	Conforms
	UV	Conforms
	Should show positive reaction of chlorides and bromides	Conforms
Related substance	Single impurity ≤0.5% Total impurities ≤1.0%	Conforms Conforms
Moisture content	3.0%~~4.0%	3.7%
Residue on ignition	≤0.1%	Conforms
Heavy metal	≤10ppm	Conforms
Residual solvents	Acne NMT 0.4%	0.02%
Assay	99%~101%	99.6%

 

Certifications

 

 

Packaging & Shipping

 

By Express	By Air	By Sea
Suitable for under 50kg	Suitable for more than 50kg	Suitable for more than 500kg
Fast: 3-7 days	Fast: 5-9 days	slow: 10-30 days
High cost	Medium cost	Low cost
Door to door service	Port to port service	Port to port service

 

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Why Choose us

Business Type: Manufacturer
Location: Shandong, China (Mainland)
Main Products:
Antifungal,Osteoporosis,Anticancer,Psychiatric,Antidiabetics&Antihypertensive,Anesthesia,Cardio-Cerebral -Vascular,Urinary system and so on ,also intermediate chemicals
Total Employees: 50 - 100 People
Total Annual Revenue: US$2.5 Million - US$5 Million
Year Established: 2011
Jinan Jianfeng Chemical Co.,Ltd .is a leading research-driven family-managed pharmaceutical company. In the principle of "Quality Oriented", Jianfeng  passed the certification of ISO9001:2008 Quality Management System. The products meet USP, EP, JP and CP standards and are available not only in China but also in the US, Germany, Canada, Japan, etc. To meet market demands, Jianfeng set up one R&D center, two GMP workshops and three pharmaceutical & chemical factories.
"Honesty, practicality, innovation, development" are our values. Jianfeng would like to cooperate with you with high quality products and competitive price.
 

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